Advantage II


EntirelyPets Pharmacy

Fast-Acting Flea Protection with Monthly Topical Application

Advantage II is a trusted monthly topical flea treatment for dogs and cats. It works through contact, killing fleas at every life stage — adults, larvae, and eggs — helping to stop infestations fast and prevent reinfestation.

What Is Advantage II?

Advantage II uses two active ingredients — imidacloprid and pyriproxyfen — to quickly kill fleas and disrupt their life cycle. It’s a waterproof formula that remains effective even after bathing or swimming. Available for multiple weight ranges and species (dogs or cats).

Key Benefits

Pros

  • Effective across all flea life stages
  • No prescription required
  • Waterproof and long-lasting
  • Trusted by vets and pet parents

Cons

  • Does not protect against ticks
  • Some pets may experience skin sensitivity
  • Requires monthly reapplication

How It Works

Advantage II uses imidacloprid and pyriproxyfen to kill fleas through contact—no biting required. Imidacloprid targets the nervous system of adult fleas, while pyriproxyfen acts as an insect growth regulator, halting development of eggs and larvae. The topical spreads through natural skin oils and remains effective for up to 30 days.

Who It’s For

Advantage II is ideal for pet owners seeking fast, non-oral flea control for dogs or cats. It’s a top choice for households needing consistent monthly protection, especially those with pets sensitive to oral medications. Not recommended for pets under 8 weeks of age or for animals with known sensitivities to the active ingredients.

Real-World Use

Advantage II is a top pick for pet parents seeking fast, effective flea control without pills or vet visits. It’s easy to apply and widely used as part of a routine monthly prevention plan — especially in multi-pet homes.

Flea protection made simple — Advantage II delivers fast relief and lasting results with one monthly application.

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